Table 3.
Clinicopathological features | N. | PTEN protein expression | P-value | ||||
---|---|---|---|---|---|---|---|
0 | 1+ | 2+ | 3+ | PR (%) | |||
Total cases (cancerous) | 125 | 41 | 34 | 37 | 13 | 67.2 | |
Age | 0.943 | ||||||
< 50 | 18 | 6 | 4 | 6 | 2 | 66.7 | |
≥ 50 | 107 | 35 | 30 | 31 | 11 | 67.2 | |
Sex | 0.251 | ||||||
Female | 55 | 15 | 16 | 18 | 6 | 72.7 | |
Male | 70 | 26 | 18 | 19 | 7 | 62.8 | |
Tumor size (cm) | 0.007 | ||||||
≤ 5 | 79 | 19 | 23 | 27 | 10 | 76 | |
> 5 | 46 | 22 | 11 | 10 | 3 | 52.2 | |
TNM Stage | 0.011 | ||||||
I & II | 25 | 3 | 6 | 12 | 4 | 88 | |
III & IV | 100 | 38 | 28 | 25 | 9 | 62 | |
Tumor Differentiation | 0.534 | ||||||
High | 65 | 19 | 17 | 18 | 11 | 70.8 | |
Moderate | 49 | 17 | 14 | 16 | 2 | 65.3 | |
Low | 11 | 5 | 3 | 3 | 0 | 54.5 | |
PTEN Promoter methylation | 0.013 | ||||||
Methylated | 39 | 18 | 15 | 4 | 2 | 53.8 | |
Unmethylated | 86 | 23 | 19 | 33 | 11 | 73.2 |
PR positive rate, TNM Tumor, Node Metastases staging system