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. 2016 Jan 19;23:8. doi: 10.1186/s12929-016-0223-x

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© Wu et al. 2016

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 1 — Application of biopanning with phage-displayed random peptide libraries. Random peptide libraries displayed on phages can be used for a number of target candidates, including purified antibodies (B-cell epitopes), receptors (agonists or antagonists), enzymes (enzyme inhibitors), and carbohydrates (antigen-mimetic peptides). After three to five rounds of biopanning, specific individual phage clones are selected and analyzed