Table 3.
Genetic and allelic distribution of SNPs among the Fulani and Dogon
| SNP | Fulani (n = 63) | Dogon (n = 179) | P value | ||
|---|---|---|---|---|---|
| N | % | N | % | ||
| FcγRIIB (rs1050519) | |||||
| GG | 41 | 65.08 | 139 | 77.65 | |
| GT | 16 | 25.40 | 32 | 17.88 | |
| TT | 6 | 9.52 | 8 | 4.47 | |
| Frequency of mutant allele | 22 | 34.92 | 40 | 22.35 | 0.064 |
| FcγRIIC (rs3933769) | |||||
| CC | 15 | 23.81 | 113 | 63.13 | |
| CT | 42 | 66.7 | 50 | 27.93 | |
| TT | 6 | 9.52 | 16 | 8.94 | |
| Frequency of mutant allele | 48 | 76.19 | 66 | 36.87 | <0.0001* |
| FcγRIIIA (rs396991) | |||||
| AA | 40 | 63.49 | 108 | 60.34 | |
| AG | 19 | 30.16 | 57 | 31.84 | |
| GG | 4 | 6.35 | 14 | 7.44 | |
| Frequency of mutant allele | 23 | 36.51 | 71 | 39.66 | 0.0043* |
Genotypic and mutant allele distribution in Fulani, Dogon and entire study population
p Values are for mutant allele comparisons between Fulani and Dogon
* Statistically significant differences (p < 0.05)