[Table/Fig-1]:
Treatment (group |
Dose (Oral) |
Urine (volume(ml) |
Na+ (mEq/L) |
K + (mEq/L) |
Cl – (mEq/L) |
---|---|---|---|---|---|
Control | 25 ml/kg |
2.93+0.20 | 112.00+2.52 | 48.75+1.20 | 160.50+4.32 |
Standard | 20 mg/kg |
8.43+0.89 | 140.33+1.86 | 90.70+1.44 | 314.50+12.48 |
Test- 1 | 100 (mg/kg |
5.80+0.35* | 131.50+1.64* | 55.61+3.15* | 263.00+4.14* |
Test- 2 | 200 mg/kg |
5.23+0.40* | 128.16+4.95* | 66.31+3.41* | 170.33+7.89* |
Test- 3 | 400 mg/kg |
5.16+0.56* | 120.16+3.31 | 81.93+3.60* | 155.50+3.21 |
Values are in Mean+SD and the data was analysed by one-way ANOVA followed by Dunnett’s test. *p-value < 0.05 when compared with control and treated groups.