[Table/Fig-1]:
Major enzymes of leech saliva and their functions [7]
Enzymes /substances | Function | |
---|---|---|
1. | Hirudin | The most well known enzyme, a powerful anticoagulant in existence, than heparin |
2. | Bdellin | A protease inhibitor thus acts as anti-inflammatory. |
3. | Apyrase | A powerful platelet anti-aggregate factor thus making blood flow more fluid. |
4. | Eglin | It is also an inhibitor of inflammation but at the same time it is an anti-oxidant. |
5. | Destabilase | The enzyme has very powerful platelet anti-aggregating activity which acts by dissolving the blood clots, thus opening up very exciting therapeutic avenues. |
6. | Hyaluronidase | It acts both as factor for diffusion and as an antibiotic. |
7. | Lipase and Esterase | Used for hyperlipidaemia. |
8. | Anti-elastase | This substance acts by limiting the action of Elastases which degrade cutanous elastin particularly at the level of skin. |