Table 1.
Comparison of clinical characteristics according to G‐395A and F352V genotypes. Fisher's exact test
| F352V (rs9536314) | G‐395A (rs1207568) | |||||
|---|---|---|---|---|---|---|
| VV + FV (53) | FF (52) | P | GA + AA (64) | GG (41) | P | |
| AS | 25 (47.2) | 22 (42.3) | NS | 27 (42.2) | 19 (46.3) | NS |
| VC | 16 (30.2) | 11 (21.2) | NS | 16 (25) | 11 (26.8) | NS |
| DM | 26 (49.1) | 20 (38.5) | NS | 34 (53.1) | 13 (31.7) | <0.05 |
| DP | 30 (56.6) | 34 (65.4) | NS | 41 (64.1) | 24 (58.5) | NS |
| HT | 38 (71.7) | 28 (53.8) | NS | 37 (57.8) | 28 (68.3) | NS |
| AT | 48 (90.5) | 36 (69.2) | <0.01 | 53 (82.8) | 32 (78) | NS |
| CAD | 41 (77.4)a | 32 (61.5) | 0.08 | 47 (73.4) | 27 (65.9) | NS |
| LVH | 16 (30.2) | 14 (26.9) | NS | 16 (25) | 14 (34.1) | NS |
a
All 12 subjects with VV genotype presented CAD.
AS: aortic stenosis; VC: valvular calcification; DM: diabetes mellitus; DP: dyslipidaemia; HT: hypertension; AT: atherosclerosis; CAD: coronary artery disease; LVH: left ventricular hypertrophy; NS: not significative.