Table 1.
Concentration of 5-HT, 5-HT2AR, and SERT in serum and platelet lysate in different group (control group, depression group, MI group, depression + MI group)
| Groups | n | Mean ± SD | P |
|---|---|---|---|
| Serum 5-HT | |||
| Control | 6 | 352.98 ± 13.73 | 0.000* |
| Depression | 6 | 303.25 ± 9.99 | |
| MI | 6 | 381.78 ± 14.17 | 0.001* |
| 0.000† | |||
| Depression + MI | 6 | 360.62 ± 11.40 | 0.326* |
| 0.000† | |||
| 0.009‡ | |||
| Platelet 5-HT | |||
| Control | 6 | 500.29 ± 20.91 | 0.000* |
| Depression | 6 | 380.40 ± 17.90 | |
| MI | 6 | 387.75 ± 22.28 | 0.000* |
| 0.571† | |||
| Depression+MI | 6 | 246.40 ± 18.99 | 0.000* |
| 0.000† | |||
| 0.000‡ | |||
| Platelet 5-HT2AR | |||
| Control | 6 | 273.66 ± 16.90 | 0.000* |
| Depression | 6 | 370.75 ± 14.75 | |
| MI | 6 | 393.47 ± 15.73 | 0.000* |
| 0.037† | |||
| Depression+MI | 6 | 446.66 ± 18.86 | 0.000* |
| 0.000† | |||
| 0.000‡ | |||
| Serum SERT | |||
| Control | 6 | 490.56 ± 28.50 | 0.047* |
| Depression | 6 | 527.51 ± 28.32 | |
| MI | 6 | 602.02 ± 23.32 | 0.000* |
| 0.000† | |||
| Depression + MI | 6 | 734.76 ± 29.59 | 0.000* |
| 0.000† | |||
| 0.000‡ | |||
| Platelet SERT | |||
| Control | 6 | 708.62 ± 51.15 | 0.000* |
| Depression | 6 | 906.38 ± 51.84 | |
| MI | 6 | 897.33 ± 60.34 | 0.000* |
| 0.773† | |||
| Depression + MI | 6 | 1030.17 ± 58.73 | 0.000* |
| 0.001† | |||
| 0.001‡ |
*Contrast to control group; †Contrast to depression group; ‡Contrast to MI group. MI: Myocardial infarction; SD: Standard deviation; SERT: Serotonin transporter; 5-HT2AR: 5-HT2A receptor.