Table 5.
The VHL mutation status analysis
| Variables | VHL gene | P | |
|---|---|---|---|
| Mutation | Wild-type | ||
| Gender | |||
| Male | 8 | 38 | 0.645 |
| Female | 3 | 10 | |
| Age (years) | |||
| ≤60 | 8 | 31 | 0.610 |
| >60 | 3 | 17 | |
| Pathological grade | |||
| G1 or G2 | 5 | 31 | 0.245 |
| G3 | 6 | 17 | |
| Number disease sites | |||
| 2 or less | 9 | 39 | 0.965 |
| >2 | 2 | 9 | |
| Hypertension | |||
| No | 3 | 16 | 0.700 |
| Yes | 8 | 32 | |
| Handfoot skin reaction | |||
| No | 1 | 18 | 0.071 |
| Yes | 10 | 30 | |
| Hypothyroidism | |||
| No | 4 | 28 | 0.191 |
| Yes | 7 | 20 | |
| Hyperlipidemia | |||
| No | 1 | 17 | 0.090 |
| Yes | 10 | 31 | |
| Fatigue | |||
| No | 4 | 22 | 0.572 |
| Yes | 7 | 26 | |
| VEGFR-1 | |||
| Negative | 2 | 17 | 0.274 |
| Positive | 9 | 31 | |
| VEGFR-2 | |||
| Negative | 3 | 14 | 0.901 |
| Positive | 8 | 34 | |
| VEGFR-3 | |||
| Negative | 5 | 33 | 0.149 |
| Positive | 6 | 15 | |
| KIT | |||
| Negative | 7 | 31 | 0.953 |
| Positive | 4 | 17 | |
VHL: Von Hippel-Lindau; VEGFR: Vascular endothelial growth factor receptors.