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. 2015 Aug 20;128(16):2220–2227. doi: 10.4103/0366-6999.162507

Figure 1.

Figure 1

Impaired olfaction in 5XFAD mice shown by buried food pellet and olfactory maze tests (5XFAD mice, 3 months of age, n = 7, 6 months of age, n = 7; wild-type counterparts, 3 months of age, n = 7, 6 months of age, n = 7). At 3 months, no significant difference in the latency between wild-type and 5XFAD mice on each trial day. At 6 months, a significantly greater latency time for 5XFAD mice on each trial day when compared with wild-type mice (day 1 *P = 0.0012, day 2 *P = 0.0031, day 3 *P = 0.0160 in buried food pellet recovery test; day 1 *P = 0.0002, day 2 *P < 0.0001, day 3 *P = 0.0045 in olfaction maze test). No significant difference in the latency time was found in the visible food pellet test across the groups.