Table 1.
Patients (N = 56) | Control subjects (N = 29) | |
---|---|---|
Age, yr | 62 (53–68) | 56 (49–58) |
Males/females | 2/54 | 3/26 |
Disease duration, yr | 5 (7–24) | |
Current/prior/never smokers | 7/21/28 | 2/27 |
Fulfilled AECG criteria for pSS | 100 % | |
Anti-SS-A–positive | 71 % | |
Anti-SS-B–positive | 39 % | |
ANA-positive | 73 % | |
RF-positive | 50 % | |
Lip biopsy focus score ≥1 | 89 % | |
ESSDAI | 7 (2–7) | |
ESSPRI | 6 (5–8) | |
ESR, mm/h (n = 53) | 17 (11–28) | |
IgG, g/L | 13 (10–16) | |
C3, g/L | 1.0 (0.9–1.2) | |
C4, g/L | 0.18 (0.13–0.21) |
AECG American-European Consensus Group, ANA anti-nuclear antibodies, anti-SS-A anti-Sjögren’s syndrome–related antigen A, anti-SS-B anti-Sjögren’s syndrome–related antigen B; C3 complement component 3, C4 complement component 4, ESR erythrocyte sedimentation rate, ESSDAI European League Against Rheumatism Sjögren’s Syndrome Disease Activity Index, ESSPRI European League Against Rheumatism Sjögren’s Syndrome Patient-Reported Index, IgG immunoglobulin G, pSS primary Sjögren’s syndrome, RF rheumatoid factor
Values are given as median (interquartile range), number or percentage