Table 1.
Patient characteristics at baseline
Characteristic | All patients (n = 444) |
---|---|
Age, years | 56.4 ± 12.7 |
Sex, female | 373 (84.0 %) |
RA duration (years) | 8.1 ± 8.5 |
Serum CRP (mg/l) | 27.6 ± 27.9 |
Tender joint count | 6 (3–11) |
Swollen joint count | 6 (3–10) |
DAS28CRP3 score | 4.6 ± 1.0 |
Disease activity | |
Mild (2.6 < DAS28 ≤ 3.2) | 31 (7.0 %) |
Moderate (3.2 < DAS28 ≤ 5.1) | 282 (63.5 %) |
Severe (DAS28 > 5.1) | 131 (29.5 %) |
Anti-TNF therapy | |
Etarnercept | 172 (38.7 %) |
Infliximab | 242 (54.5 %) |
Adalimumab | 30 (6.8 %) |
Other medications | |
Methotrexate | 354 (79.7 %) |
Prednisolone | 283 (65.1 %)*a |
Anti-TNF naïve at baseline | 419 (94.4 %) |
Switching to a new anti-TNF agent at baseline | 18 (4.1 %) |
Ever smoker | 94 (23.4 %)*b |
ACPA positive | 330 (88.7 %)*c |
RF positive | 337 (80.1 %)*d |
Results are shown as mean ± SD, median (IQR) or number (%). *Data for these variables were not available for all patients. Sample sizes were as follows a435, b402, c372, d421. RA rheumatoid arthritis, CRP C-reactive protein, Disease Activity Score in 28 joints DAS28, ACPA anti-citrullinated protein antibodies, RF rheumatoid factor