Table 1.

Treatment arms

Group assignment	Single-dose phase	Multiple-dose phase
A	Placebo	Dexketoprofen/tramadol 25 mg/75 mg
B	Dexketoprofen/tramadol 25 mg/75 mg	Dexketoprofen/tramadol 25 mg/75 mg
C	Placebo	Dexketoprofen 25 mg
D	Dexketoprofen 25 mg	Dexketoprofen 25 mg
E	Placebo	Tramadol 100 mg
F	Tramadol 100 mg	Tramadol 100 mg