Nomenclature | Interleukin‐6 receptor | Interleukin‐11 receptor | Interleukin‐31 receptor | Ciliary neutrophic factor receptor |
Subunits | Interleukin‐6 receptor, α subunit (Ligand‐binding subunit), Interleukin‐6 receptor, β subunit (Other subunit) | Interleukin‐11 receptor, α subunit (Ligand‐binding subunit), Interleukin‐6 receptor, β subunit (Other subunit) | Interleukin‐31 receptor, α subunit (Ligand‐binding subunit), Oncostatin M‐specific receptor, β subunit (Other subunit) | Leukemia inhibitory factor receptor (Other subunit), Interleukin‐6 receptor, β subunit, Ciliary neurotrophic factor receptor α subunit (Ligand‐binding subunit) |
Endogenous agonists | IL‐6 (IL6, P05231) | IL‐11 (IL11, P20809) | IL‐31 (IL31, Q6EBC2) | CRCF1/CLCF1 heterodimer (CLCF1 CRLF1, O75462 Q9UBD9), ciliary neurotrophic factor (CNTF, P26441) |
Agonists | – | oprelvekin | – | – |
Antibodies | tocilizumab (Binding) (pK d 8.6) | – | – | – |