| Nomenclature | GPR146 | GPR148 | GPR149 | GPR150 | GPR151 |
| HGNC, UniProt | GPR146, Q96CH1 | GPR148, Q8TDV2 | GPR149, Q86SP6 | GPR150, Q8NGU9 | GPR151, Q8TDV0 |
| Comments | Yosten et al. demonstrated inhibition of proinsulin C‐peptide (INS, P01308)‐induced stimulation of cFos expression folllowing knockdown of GPR146 in KATO III cells, suggesting proinsulin C‐peptide as an endogenous ligand of the receptor [2103]. | – | Gpr149 knockout mice displayed increased fertility and enhanced ovulation, with increased levels of FSH receptor and cyclin D2 mRNA levels [463]. | – | GPR151 responded to galanin with an EC50 value of 2 μM, suggesting that the endogenous ligand shares structural features with galanin (GAL, P22466) [813]. |
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