Nomenclature | GPR152 | GPR153 | GPR160 | GPR161 | GPR162 |
HGNC, UniProt | GPR152, Q8TDT2 | GPR153, Q6NV75 | GPR160, Q9UJ42 | GPR161, Q8N6U8 | GPR162, Q16538 |
Comments | – | – | – | A C‐terminal truncation (deletion) mutation in Gpr161 causes congenital cataracts and neural tube defects in the vacuolated lens (vl) mouse mutant [1226]. The mutated receptor is associated with cataract, spina bifida and white belly spot phenotypes in mice [994]. Gene disruption is associated with a failure of asymmetric embryonic development in zebrafish [1085]. | – |