Nomenclature | GPR171 | GPR173 | GPR174 | GPR176 | GPR182 |
HGNC, UniProt | GPR171, O14626 | GPR173, Q9NS66 | GPR174, Q9BXC1 | GPR176, Q14439 | GPR182, O15218 |
Endogenous agonists | – | – | lysophosphatidylserine (pEC50 7.1) [825] | – | – |
Comments | GPR171 has been shown to be activated by the endogenous peptide BigLEN {Mouse}. This receptor‐peptide interaction is believed to be involved in regulating feeding and metabolism responses [621]. | – | See [819] which discusses characterization of agonists at this receptor. | – | Rat GPR182 was first proposed as the adrenomedullin receptor [904]. However, it was later reported that rat and human GPR182 did not respond to adrenomedullin [927] and GPR182 is not currently considered to be a genuine adrenomedullin receptor [722]. |