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. 2015 Dec 9;172(24):5744–5869. doi: 10.1111/bph.13348
Nomenclature GPR171 GPR173 GPR174 GPR176 GPR182
HGNC, UniProt GPR171, O14626 GPR173, Q9NS66 GPR174, Q9BXC1 GPR176, Q14439 GPR182, O15218
Endogenous agonists lysophosphatidylserine (pEC50 7.1) [825]
Comments GPR171 has been shown to be activated by the endogenous peptide BigLEN {Mouse}. This receptor‐peptide interaction is believed to be involved in regulating feeding and metabolism responses [621]. See [819] which discusses characterization of agonists at this receptor. Rat GPR182 was first proposed as the adrenomedullin receptor [904]. However, it was later reported that rat and human GPR182 did not respond to adrenomedullin [927] and GPR182 is not currently considered to be a genuine adrenomedullin receptor [722].