Nomenclature	5‐ht5a receptor	5‐ht5b receptor	5‐HT6 receptor	5‐HT7 receptor
HGNC, UniProt	HTR5A, P47898	HTR5BP, –	HTR6, P50406	HTR7, P34969
Selective agonists	–	–	WAY‐181187 (pK i 8.7) [1663], E6801 (Partial agonist) (pK i 8.7) [769], WAY‐208466 (pK i 8.3) [135], EMD‐386088 (pIC50 8.1) [1228]	LP‐12 (pK i 9.9) [1082], LP‐44 (pK i 9.7) [1082], LP‐211 (pK i 9.2) [1083] – Rat, AS‐19 (pK i 9.2) [947], E55888 (pK i 8.6) [206]
Antagonists	–	–	–	lurasidone (pK i 9.3) [829], pimozide (pK i 9.3) [1604] – Rat, vortioxetine (pK i 6.3) [90]
Selective antagonists	SB 699551 (pK i 8.2) [366]	–	SB399885 (pK i 9) [763], SB 271046 (pK i 8.9) [224], cerlapirdine (pK i 8.9) [358], SB357134 (pK i 8.5) [225], Ro 63‐0563 (pK i 7.9–8.4) [168, 1754]	SB269970 (pK i 8.6–8.9) [1874], SB656104 (pK i 8.7) [531], DR‐4004 (pK i 8.7) [615, 938], JNJ‐18038683 (pK i 8.2) [177], SB 258719 (Inverse agonist) (pK i 7.5) [1875]
Labelled ligands	[125I]LSD (Agonist) (pK d 9.7) [636], [3H]5‐CT (Agonist) (pK d 8.6) [636]	[125I]LSD (Agonist) (pK d 9.3) [1227] – Mouse, [3H]5‐CT (Agonist) [1965] – Mouse	[11C]GSK215083 (Antagonist) (pK i 9.8) [1462], [125I]SB258585 (Selective Antagonist) (pK d 9) [763], [3H]LSD (Agonist) (pK d 8.7) [167], [3H]Ro 63‐0563 (Antagonist) (pK d 8.3) [168], [3H]5‐CT (Agonist)	[3H]5‐CT (Agonist) (pK d 9.4) [1874], [3H]5‐HT (Agonist) (pK d 8.1–9) [93, 1793], [3H]SB269970 (Selective Antagonist) (pK d 8.9) [1874], [3H]LSD (Agonist) (pK d 8.5–8.6) [1793]