Nomenclature	D3 receptor	D4 receptor	D5 receptor
HGNC, UniProt	DRD3, P35462	DRD4, P21917	DRD5, P21918
Endogenous agonists	dopamine (pK i 6.4–7.3) [245, 545, 1653, 1778]	dopamine (pK i 7.6) [1940]	dopamine (pK i 6.6) [1823]
Agonists	pramipexole (pK i 8.4–8.7) [1273, 1653], bromocriptine (Partial agonist) (pK i 7.1–8.2) [545, 1279, 1653], ropinirole (pK i 7.7) [732], apomorphine (Partial agonist) (pK i 6.1–7.6) [245, 545, 1279, 1653, 1776]	apomorphine (Partial agonist) (pK i 8.4) [1279]	–
(Sub)family‐selective agonists	quinpirole (pK i 6.4–8) [245, 1273, 1281, 1473, 1653, 1776, 1778, 1940]	quinpirole (pK i 7.5) [1279, 1473, 1940]	A68930 (pEC50 6.6) [1381]
Selective agonists	PD 128907 (pK i 7.6–7.7) [1539, 1653]	PD168,077 (Partial agonist) (pK i 8.8) [995] – Rat, A412997 (pK i 8.1) [1319] – Rat, A412997 (pK i 8.1) [1319]	–
Antagonists	perospirone (pK i 9.6) [1776], sertindole (pK i 8–8.8) [60, 1675, 1691], prochlorperazine (pK i 8.4) [68], (‐)‐sulpiride (pK i 6.7–7.7) [545, 1776, 1860], loxapine (pK i 7.7) [1691], domperidone (pK i 7.1–7.6) [545, 1776], promazine (pK i 6.8) [246]	perospirone (pK i 10.1) [1694], sertindole (pK i 7.8–9.1) [246, 1691, 1693, 1694], sonepiprazole (pK i 8.9) [1668], loxapine (pK i 8.1) [1693]	–
(Sub)family‐selective antagonists	haloperidol (pK i 7.5–8.6) [545, 1711, 1776, 1885]	haloperidol (pK i 8.7–8.8) [1033, 1711, 1885]	SCH‐23390 (pK i 7.5–9.5) [1823], SKF‐83556 (pK i 9.4) [1823], ecopipam (pK i 8.3) [1823]
Selective antagonists	S33084 (pK i 9.6) [1278], nafadotride (pK i 9.5) [1654], PG01037 (pK i 9.2) [656], NGB 2904 (pK i 8.8) [2055], SB 277011‐A (pK i 8) [1569], (+)‐S‐14297 (pK i 6.9–7.9) [1275, 1281]	L745870 (pK i 9.4) [1020], A‐381393 (pK i 8.8) [1361], L741742 (pK i 8.5) [1609], ML398 (pK i 7.4) [138]	–
Selective allosteric modulators	SB269652 (Negative) (pK i∼9) [558]	–	–
Labelled ligands	–	[3H]spiperone (Antagonist) (pK d 9.5) [749, 1940]	[3H]SCH‐23390 (Antagonist) (pK d 9.2) [1580]
Labelled ligands	[3H]spiperone (Antagonist) (pK d 9.9) [767, 2125] – Rat, [3H]7‐OH‐DPAT (Agonist) (pK d 9.6) [1581], [3H]PD128907 (Agonist) (pK d 9) [27]	[125I]L750667 (Antagonist) (pK d 9.8) [1473], [3H]NGD941 (Antagonist) (pK d 8.3) [1533]	[125I]SCH23982 (Antagonist) (pK d 9.1) – Unknown