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. 2015 Dec 9;172(24):5956–5978. doi: 10.1111/bph.13352
Nomenclature Retinoic acid receptor‐α Retinoic acid receptor‐β Retinoic acid receptor‐γ
Systematic nomenclature NR1B1 NR1B2 NR1B3
HGNC, UniProt RARA, P10276 RARB, P10826 RARG, P13631
Agonists tretinoin (pEC50 7.8) [26] tretinoin (pEC50 7.9) [26] tretinoin (pEC50 9.7) [26]
(Sub)family‐selective agonists tazarotene (pEC50 7.2) [26] tazarotene (pEC50 9.1) [26], adapalene (pK i 7.5) [25] tazarotene (pEC50 7.4) [26], adapalene (pK i 6.9) [25]
Selective agonists BMS753 (pK i 8.7) [53], Ro 40‐6055 (pK d 8.2) [33], tamibarotene (pIC50 6.9) [65, 108, 146] AC261066 (pEC50 7.9–8.1) [90], AC55649 (pEC50 6.5–7.3) [90] AHPN (pK i 7.1) [25]
Selective antagonists Ro 41‐5253 (pIC50 6.3–7.2) [2, 70] MM 11253 [77]