| Nomenclature | Farnesoid X receptor | Farnesoid X receptor‐β | Liver X receptor‐α | Liver X receptor‐β |
| Systematic nomenclature | NR1H4 | NR1H5 | NR1H3 | NR1H2 |
| HGNC, UniProt | NR1H4, Q96RI1 | NR1H5P, – | NR1H3, Q13133 | NR1H2, P55055 |
| Potency order | chenodeoxycholic acid>lithocholic acid, deoxycholic acid [93, 116] | – | 20S‐hydroxycholesterol, 22R‐hydroxycholesterol, 24(S)‐hydroxycholesterol>25‐hydroxycholesterol, 27‐hydroxycholesterol [80] | 20S‐hydroxycholesterol, 22R‐hydroxycholesterol, 24(S)‐hydroxycholesterol>25‐hydroxycholesterol, 27‐hydroxycholesterol [80] |
| Endogenous agonists | – | lanosterol (pEC50 6) [114] – Mouse | – | – |
| Selective agonists | GW4064 (pEC50 7.8) [95], obeticholic acid (pEC50 7) [117], fexaramine (pEC50 6.6) [36] | – | – | – |
| Selective antagonists | guggulsterone (pIC50 5.7–6) [161] | – | – | – |
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