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. 2015 Dec 9;172(24):6110–6202. doi: 10.1111/bph.13355
Nomenclature BGT1 TauT CT1
Systematic nomenclature SLC6A12 SLC6A6 SLC6A8
HGNC, UniProt SLC6A12, P48065 SLC6A6, P31641 SLC6A8, P48029
Endogenous substrates GABA, betaine β‐alanine, taurine, GABA [9] creatine
Stoichiometry 3Na+: 1 (or 2) Cl: 1GABA 2Na+: 1Cl: 1 taurine Probably 2Na+: 1Cl: 1 creatine
Selective inhibitors NNC052090 (pK i 5.9) [473] – Mouse, (R/S) EF‐1500 (pIC50 4.9), (R)‐EF‐1520 (pIC50 3.7–4.7), (S)‐EF‐1520 (pIC50 3.6–4.5), LU32‐176B (pIC50 4) [512] – Mouse