Nomenclature | Organic anion transporter 1 | Organic anion transporter 2 | Organic anion transporter 3 |
Systematic nomenclature | SLC22A6 | SLC22A7 | SLC22A8 |
Common abreviation | OAT1 | OAT2 | OAT3 |
HGNC, UniProt | SLC22A6, Q4U2R8 | SLC22A7, Q9Y694 | SLC22A8, Q8TCC7 |
Substrates | aminohippuric acid, non‐steroidal anti‐inflammatory drugs | aminohippuric acid, PGE2, non‐steroidal anti‐inflammatory drugs | estrone‐3‐sulphate [294], aminohippuric acid [294], cimetidine [294], ochratoxin A [294] |
Stoichiometry | Unknown | Unknown | Unknown |
Inhibitors | probenecid (Inhibition of urate transport by human SCL22A6.) (pIC50 4.9) [239] | – | – |