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. 2015 Dec 9;172(24):6110–6202. doi: 10.1111/bph.13355
Nomenclature Organic anion transporter 1 Organic anion transporter 2 Organic anion transporter 3
Systematic nomenclature SLC22A6 SLC22A7 SLC22A8
Common abreviation OAT1 OAT2 OAT3
HGNC, UniProt SLC22A6, Q4U2R8 SLC22A7, Q9Y694 SLC22A8, Q8TCC7
Substrates aminohippuric acid, non‐steroidal anti‐inflammatory drugs aminohippuric acid, PGE2, non‐steroidal anti‐inflammatory drugs estrone‐3‐sulphate [294], aminohippuric acid [294], cimetidine [294], ochratoxin A [294]
Stoichiometry Unknown Unknown Unknown
Inhibitors probenecid (Inhibition of urate transport by human SCL22A6.) (pIC50 4.9) [239]