Comments |
Transports sterols and choline
phospholipids [275] |
Exhibits a broad substrate
specificity, including urate and haem, as well as multiple synthetic
compounds [275]. The
functional transporter is likely to be a homodimer, although higher
oligomeric states have also been proposed. |
Putative functional dependence
on ABCG1 |
Transports phytosterols and
cholesterol; forms an obligate heterodimer with ABCG8.
Loss‐of‐function mutations in ABCG5 are associated with sitosterolemia
(OMIM:
210250). |
Transports phytosterols and
cholesterol; forms an obligate heterodimer with ABCG5.
Loss‐of‐function mutations in ABCG8 are associated with sitosterolemia
(OMIM:
210250). |