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. 2016 Jan 15;95(2):e2454. doi: 10.1097/MD.0000000000002454

FIGURE 1.

FIGURE 1

Sequential changes and standard error of the mean of noninvasive liver indices during 12 cycles of FOLFOX chemotherapy. Changes of 4 noninvasive liver indices: (A) API, (B) APRI, (C) PSR, and (D) FIB-4 were calculated at the initial 3rd, 6th, 9th, and 12th cycles. All patients were treated with 12 cycles of FOLFOX chemotherapy. ∗P < 0.05 calculated by the difference between the changes of indices as compared with baseline by the SVI group at each point. API = age-platelet index, APRI = AST-to-platelet ratio index, FIB-4 = gibrosis-4 score, PSR = platelet-to-spleen ratio.