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. Author manuscript; available in PMC: 2017 Jan 1.
Published in final edited form as: Semin Radiat Oncol. 2015 Aug 29;26(1):51–58. doi: 10.1016/j.semradonc.2015.08.001

Table 1.

Summary of key retrospective studies evaluating role of postmastectomy radiation therapy after neoadjuvant chemotherapy.

% LRR
No. of
Patients		 Follow
up mo		 %
Clinical
Stage		 %
Complete
Response rate		 PMRT No
PMRT		 p-value
Huang19, 1974–2000 676 67 I–II 30
III 70		 14.3 11 22 0.0001
McGuire20, 1985–2004 106 62 I–II 33
III 67		 100 5 10 0.40
Garg21, 1975–2005 (age<35 years) 107 72 II 27
III 73		 17.7 12 37 0.001
Nagar22, 1985–2004 162 - cT3N0 8 4 24 <0.001
Le Scodan23, 1990–2004 134 91 II 63%
III 37%		 100% ypN0 4 12 0.12
Shim24, 1998–2009 151 57 II 60%
III 40%		 100% ypN0 2 8 0.15
*

Legend: LRR=locoregional recurrence; PMRT=postmastectomy radiation therapy