Table 1.
Baseline characteristics
| ISTp-DP group (n=515) | IPTp-DP group (n=514)* | IPTp-SP group (n=514)* | |
|---|---|---|---|
| Study site | |||
| Bondo | 153 (30%) | 153 (30%) | 154 (30%) |
| Lwak | 126 (24%) | 125 (24%) | 125 (24%) |
| Madiany | 160 (31%) | 159 (31%) | 159 (31%) |
| Siaya | 76 (15%) | 77 (15%) | 76 (15%) |
|
| |||
| Age (years) | 23.4 (5.9) | 23.4 (5.5) | 23.5 (6.0) |
|
| |||
| Gravidity | |||
| Primigravid or secundigravid (first or second pregnancy) | 267 (52%) | 263 (51%) | 292 (57%) |
| Multigravid (third pregnancy or more) | 248 (48%) | 251 (49%) | 222 (43%) |
|
| |||
| Gestational age (weeks)† | 22.9 (47) | 23.0 (4.0) | 22.8 (4.4) |
|
| |||
| Weight (kg) | 61.1 (8.3) | 61.8 (9.3) | 61.5 (9.1) |
|
| |||
| Height (cm) | 164.1 (6.8) | 164.3 (67) | 164.3 (6.9) |
|
| |||
| Educational status rank | |||
| Low | 121 (23%) | 119 (23%) | 118 (23%) |
| Medium | 231 (45%) | 222 (44%) | 224 (44%) |
| High | 162 (32%) | 168 (33%) | 169 (33%) |
|
| |||
| SES index | |||
| Low | 181 (35%) | 162 (32%) | 173 (34%) |
| Medium | 174 (34%) | 170 (33%) | 167 (33%) |
| High | 159 (31%) | 179 (35%) | 171 (33%) |
|
| |||
| Slept under a longlasting insecticide-treated net during the previous night | 292 (57%) | 292 (57%) | 294 (57%) |
|
| |||
| Haemoglobin (g/L) | 105 (160) | 106 (15) | 105 (15) |
|
| |||
| Anaemia (haemoglobin <110 g/L) | 325 (63%) | 302 (59%) | 307 (60%) |
|
| |||
| Malaria infection (by PCR) | 178/513 (35%) | 157/509 (31%) | 168/510 (33%) |
|
| |||
| Symptomatic malaria infection (by microscopy) | 14 (3%) | 8 (2%) | 4 (<1%) |
|
| |||
| Syphilis infection | 7/515 (1%) | 3/514 (<1%) | 7/514 (1%) |
Data are n (%), mean (SD), or n/N (%), unless otherwise specified. ISTp-DP=intermittent screening and treatment during pregnancy with dihydroartemisinin–piperaquine. IPTp-DP=intermittent preventive treatment during pregnancy with dihydroartemisinin–piperaquine. IPTp-SP=intermittent preventive treatment during pregnancy with sulfadoxine–pyrimethamine. SES=socioeconomic status.
*
Two women were excluded in the IPTp-DP group and one woman was excluded in the IPTp-SP group because of withdrawal of consent before baseline intervention was given (n=1), loss of study data file (n=1), and enrolment violation (n=1).
†
Determined by history of last menstrual period and physical examination.