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. 2015 Nov 12;17(1):27–36. doi: 10.15252/embr.201540614

Figure 3. Cholesteryl ester production in ApoE ACM‐treated cells.

Figure 3

  1. Cholesteryl ester synthesis, as measured by 3H‐oleate incorporation. Note increased CE in ApoE4‐treated cells, whereas there was essentially no difference in triglyceride (TAG) production (mean ± SE; n = 3, with 3 replicates/experiment). *P < 0.05, † P = 0.06 vs. E3.
  2. Comparison of 3H‐oleate incorporation in ApoE ACM‐treated WT and Mfn2‐KO MEFs (mean ± SE; n = 3, with 5 replicates/experiment). *P < 0.05 vs. E3.
  3. ApoE ACM‐treated fibroblasts were stained with LipidTox green neutral lipid stain, and lipid droplets were visualized (example at left) and counted (right). Note significantly more lipid droplets in ApoE4‐treated cells (mean ± SD, n = 3). *P < 0.05 vs. E3.