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. Author manuscript; available in PMC: 2016 Dec 14.
Published in final edited form as: Angew Chem Int Ed Engl. 2015 Nov 13;54(51):15478–15482. doi: 10.1002/anie.201508310

Figure 1.

Figure 1

Structure of C. roseus IRIS+NADPH and a comparison with D. lanata progesterone 5β-reductase. A) stereo view of IRIS in complex with NADPH (PDB ID: 5DBF). B) Superimposition of IRIS+NADPH structure (cyan) and progesterone 5β-reductase (PDB ID: 2V6G[6]) in complex with NADP+ (yellow).