Figure 1.
Structure of C. roseus IRIS+NADPH and a comparison with D. lanata progesterone 5β-reductase. A) stereo view of IRIS in complex with NADPH (PDB ID: 5DBF). B) Superimposition of IRIS+NADPH structure (cyan) and progesterone 5β-reductase (PDB ID: 2V6G[6]) in complex with NADP+ (yellow).