Table 3. Standardized neuropsychological composites for PD and non-PD peers with mean, standard deviation, and minimum/maximum scores shown.
PD (n = 40) | Non-PD (n = 40) | t | p-value | |
---|---|---|---|---|
Attention | 0.31± 0.69, -1.39/2.12 | 0.38±0.73, -1.39/1.51 | 0.40 | 0.69 |
P. Speed | -0.48±0.61, -1.76/0.83 | 0.16±0.47, -0.58/1.27 | 5.25 | <0.001* |
W. Memory | 0.34±0.51, -0.59/1.77 | 0.87±0.57, -0.45/1.92 | 4.42 | <0.001* |
Inhibition | 0.07±0.68, -1.25/1.60 | 0.21/0.69, -1.10/1.45 | 1.12 | 0.27 |
Reasoning | 0.43±0.84, -0.93/2.52 | 0.78/0.50, -0.36/1.76 | 2.28 | 0.03 |
Language | 0.28±0.71, -1.17/1.73 | 0.55±0.67, -0.63/2.30 | 1.77 | 0.08 |
Visual | 0.15±0.83, -2.50/1.34 | 0.50±0.59, -0.64/1.59 | 2.91 | 0.03 |
Memory | 0.75±0.77, -0.67/2.33 | 1.15±0.55, 0.11/2.11 | 2.67 | 0.01 |
Motor | -0.57±1.12, -2.50/1.85 | -0.47±0.67, -1.80/1.25 | 0.48 | 0.63 |
W. Memory = Working Memory; P. Speed = Processing Speed;
*Significant after Bonferroni correction. See S1 Table for the composite subtest raw and standardized scores by group.
Note: Further examination of the motor speed scores showed that group motor tapping scores were normally distributed (skewness; PD = 0.493; non-PD = 0.029), but different in range. For PD: although fifteen of the participants (38%) scored within the below average to impaired range, 10% (4 / 40) scored in the superior range. These superior scores associated with lower LED metrics (three had LED < 400; one of 700) and a disease range of 3 to 8 years. By contrast, for the non-PD peers 10% (4/40) scored in the below average with none in the superior range. Removing the four individuals with PD who had superior finger tapping scores showed a trend for finger tapping difference (t(73) = 1.78, p = .079; PD mean = -0.79).