Fig 7. IL-12 promoted E/C peptide-induced IL-21 production.

(A) PFCs were cultured in the presence of medium; with IL-6, IL-12 or IL-27 alone; with E/C peptides; or with E/C peptides plus cytokines. The number of IL-21-producing cells was determined by ELISPOT. A representative result is shown. (B) Statistical results from four independent experiments are shown. *p<0.05; *** p<0.001; N.S., not significant.