Skip to main content
. 2016 Jan 19;11(1):e0146969. doi: 10.1371/journal.pone.0146969

Fig 5. Compound C significantly inhibits transcriptional expression of AgRP and Cry1, but not Cpt1c and Ogt.

Fig 5

After serum starvation, mHypoE-37 cells were pre-treated with either vehicle or 25 μM Compound C, followed by replacement of the media with either 0.5 or 5.5 mM glucose in the absence or presence of 12.5 μM CC. This was considered time 0. RNA was harvested at indicated time points. Shown are mRNA levels relative to Histone3a mRNA levels. Plotted are mean values ± SEM of 4 independent experiments. *: p<0.05; **:p<0.01 as determined by one-way ANOVA followed by Tukey’s post-hoc test. N.s.: not significant.