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. Author manuscript; available in PMC: 2016 Nov 1.
Published in final edited form as: Thromb Res. 2015 Sep 26;136(5):966–973. doi: 10.1016/j.thromres.2015.09.016

Figure 2.

Figure 2

Figure 2

Figure 2 displays the Receiver Operating Characteristic (ROC) curves for the unweighted genetic risk scores (GRS) and moderate plus severe venous disease by race/ethnicity. The y-axis corresponds to the sensitivity, and the x-axis corresponds to one minus the specificity. The red curve represents the base model, which contains age, sex, weight, waist, ever smoking, time sitting, time walking, regular movement, hypertension, flat feet, previous leg injury, previous hernia surgery. The blue curve represents the addition of the unweighted 33-SNP GRS to the base model. The green curve represents the addition of the unweighted 5-SNP GRS to the base model. P-values for the comparison of the c-statistics for the curves are presented in the upper left hand corner.