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. 2016 Jan 19;11(1):e0147027. doi: 10.1371/journal.pone.0147027

Fig 5. DBGGA pathway analysis on time-shifted data.

Fig 5

(A) Summary table of significantly activated or repressed cellular pathways (Bayesian score ≥|2.24|) on time shifted data. Perturbation of cellular pathways and constituent genes are reported. (B-C) Heat map representation of significantly perturbed pathways at times pre-serum neutralization (pSN). Red color indicates activation, green color indicates repression. Intensity of color represents amplitude of perturbation. Analyses are oriented to the Early Phase (time –6, –5, –4, –3 pSN) (B) or the Late Phase (time –2, –1, 0, 1 pSN) (C) to identify significant pathway perturbations at different periods during the vaccine response.