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. 2016 Jan 19;11(1):e0146966. doi: 10.1371/journal.pone.0146966

Fig 1. Dose Response Curves for Agonist-Induced Behavioral Response.

Fig 1

The D2 agonist, quinpirole, stimulates greater locomotor (A) and stereotypic (B) behavior in adolescents (P32) than adults (P90). The selective D1[Gs] agonist, SKF83822, stimulates more locomotor (C) and stereotypic (D) behavior in adults than adolescents. While there are no significant age differences locomotor response to the selective D1[Gq] agonist, SKF83959 (E), 3.0mg/kg SKF83959 stimulates more stereotypy in adolescents than adults (F). Significant age difference, *p<0.05, **p<0.01; n = 6–8 per group.