Fig 6. Effect of camphene on the esterification of fatty acids into triglycerides.
On day 7, HepG2 cells were incubated for 24 h with each compound in medium containing 10% (v/v) human LPDS. The cells received camphene (25, 50 and 100 μM), mevinolin (37 μM) or atorvastatin (10 μM). Four hours prior to the end of the incubation period, the cells were pulse-labeled with [14C]-oleic acid, sodium salt. The incorporation of oleate into triglycerides was determined as described. Results were normalized to the amount of cellular protein and expressed in percent of the respective control incubations. Results are from three independent experiments in triplicates and expressed as the mean ± SD. Results not statistically significant vs control, ns (non significant) by Student-Newmann-Keuls test.