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. Author manuscript; available in PMC: 2016 Nov 15.
Published in final edited form as: Bioorg Med Chem Lett. 2015 Sep 30;25(22):5203–5207. doi: 10.1016/j.bmcl.2015.09.066

Figure 4. Cytotoxicity and hemolytic activity of PSPC.

Figure 4

(A) The viability of HEK-293 cells was measured after treatment with serially diluted concentrations (1–64 μg/ml) of PSPC or the mitochondrial toxin rotenone (positive control). Cell viability was measured spectrophotometrically by detecting degradation of WST-1 dye into formazan by viable cells, which produces measurable color.

(B) Sheep erythrocytes were treated with serial dilutions of Triton X-100 (.001–1%) or PSPC (0.063–64 μg/ml).