Table 4. Frequencies of alleles and genotypes of rs842467/REL polymorphisms in patients with skin lesions and controls.
| SNP | GenotypeAllele | Cases (N = 481) | Controls (N = 1074) | P-value | Pc | P-valuea | Pca | OR (95% CI) |
|---|---|---|---|---|---|---|---|---|
| rs842647 | AA | 6 (1.25) | 21 (1.96) | 0.32 | NS | 0.37 | NS | 0.63 (0.25–1.58) |
| AG | 73 (15.18) | 239 (22.25) | 0.0013 | 0.031 | 0.0022 | NS | 0.63 (0.47–0.83) | |
| GG | 402 (83.57) | 814 (75.79) | 0.00059 | 0.014 | 0.0012 | 0.029 | 1.63 (1.23–2.15) | |
| A | 85 (8.84) | 281 (13.08) | 0.00068 | 0.016 | 0.0014 | 0.034 | 0.64 (0.50–0.83) | |
| G | 877 (91.16) | 1,867 (86.92) | 0.00068 | 0.016 | 0.0014 | 0.034 | 1.55 (1.20–2.01) |
Pc: Bonferroni corrected P-value
Pca: Bonferroni-corrected P-value for gender adjustment
a: Gender-adjusted P-value
CI: confidence interval; OR: odds ratio