. Author manuscript; available in PMC: 2016 Jul 17.

Published in final edited form as: J Mol Biol. 2015 May 22;427(14):2396–2409. doi: 10.1016/j.jmb.2015.05.011

Table 3. Structural deviations between the free and inhibitor-bound structures.

Noted are average RMSD values for main-chain atoms (in Å)

Structure	All residues (H25-W286)	Ω-loop (E164–R179)	238-loop (S238–S242)
wild-type	0.37	0.18	0.22
G238S	0.34	0.39	0.20
R164S	0.39	1.83	0.07
R164S/ G238S	0.33	1.86	0.12