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. Author manuscript; available in PMC: 2017 Feb 1.
Published in final edited form as: Liver Int. 2015 Nov 11;36(2):158–165. doi: 10.1111/liv.12988

Table 1.

Cellular adaptive responses
Dampening reactive metabolite production or exposure
Enhanced detoxification/antioxidant defense (e.g. Nrf2)
Mitochondrial adaptation: mitophagy, biogenesis, fission/fusion
Upregulation of chaperones: ER-UPR and mitochondrial UPR
Anti-inflammatory balance (innate immunity)
Regeneration