Table 1.
Characteristics of Analyzed Patients Undergoing Coronary Artery Bypass Surgery during the Study Period
| Variable | Value* |
|---|---|
| Age, in years | 63.5 (56-81) |
| Gender, n (%) | |
| Males | 41 (74.55) |
| Females | 14 (25.45) |
| Race, n (%) | |
| Caucasian | 47 (85.45) |
| African-American | 5 (9.09) |
| Other | 3 (5.46) |
| P16 mRNA levels in PBTLs (log2-transformed) | 4.71 (1.10-6.82) |
| Baseline P16 mRNA levels in PBTLs, n (%) | |
| < 4.71 log2-transformed p16INK4a levels | 23 (41.82) |
| ≥ 4.71 log2-transformed p16INK4a levels | 24 (43.64) |
| Missing | 8 (14.55) |
| Baseline p16 protein level in LIMA/ p16 protein level in aorta | 0.49 (0.26-1.05) |
| IL-6 levels, in pg/ml | 2.66 (0.59-18.48) |
| Cerebral oximetry, in % | 63.5 (39-80) |
| Augmentation index, in % | 26 (5-79) |
| Charlson comorbidity index | 2 (0-12) |
| Myocardial infarction, n (%) | 12 (21.82) |
| Congestive heart failure, n (%) | 2 (3.64) |
| Chronic pulmonary disease, n (%) | 9 (16.36) |
| Diabetes mellitus, n (%) | 19 (34.55) |
| Moderate or severe renal disease, n (%) | 3 (5.45) |
| Baseline Frailty, n (%) | |
| Non-frail | 10 (18.18) |
| Prefrail | 28 (50.91) |
| Frail | 17 (30.91) |
| Smoking, n (%) | |
| ≤ 5 pack-years | 24 (43.64) |
| > 5 pack-years | 31 (56.36) |
| Exercise, n (%) | |
| ≤ 240 minutes/ month | 32 (58.18) |
| > 240 minutes/ month | 23 (41.82) |
| Duration of hospital stay, days | 6 (3-27) |
| Duration of ICU stay, hours | 33 (7-174) |
*
Continuous variables are presented as median (range), and categorical variables are presented as number of participants (%)
Abbreviations: PBTLs Peripheral Blood T-Lymphocytes; LIMA Left Internal Mammary Artery; IL-6 Interleukin 6; ICU Intensive Care Unit