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. Author manuscript; available in PMC: 2017 Feb 10.
Published in final edited form as: Int J Pharm. 2015 Nov 28;498(0):12–22. doi: 10.1016/j.ijpharm.2015.11.045

Table 1.

Formulation composition, droplet size, polydispersity index and stability of self-emulsifying nanoemulsion

Formulation Code Oil Surfactant Cosurfactant Surfactant:Cosurfactant
(w/w)		 Ratio
(Smix:Oil)		 Droplet Size
(nm)		 PI Stability
(RT)
(Days)
SENE – 1 Capmul PG8 Tween 80 PEG 400 6:4 9:1 9.231 0.155 –
SENE – 2 Capmul PG8 Tween 80 PEG 400 6:4 8:2 93.36 0.273 180
SENE – 3 Capmul PG8 Tween 80 PEG 400 6:4 7:3 131.2 0.259 180 +
SENE – 4 Capmul PG8 Tween 80 PEG 400 6:4 6:4 189.3 0.362 35
SENE – 5 Capmul PG8 Tween 80 PEG 400 6:4 5:5 202.1 0.348 30
SENE – 6 Capmul PG8 Tween 80 PEG 400 6:4 4:6 297.6 0.326 7
SENE – 7 Capmul PG8 Tween 80 PEG 400 6:4 3:7 >500 0.432 3
SENE – 8 Capmul PG8 Tween 80 PEG 400 6:4 2:8 PS – –
SENE – 9 Capmul PG8 Tween 80 PEG 400 6:4 1:9 PS – –

Smix refers to weight ratios of surfactant and cosurfactant. Samples were made at a constant premix (mixture of oil and Smix)-to-water ratio of 1:10 (w/w). PI value refers to polydispersity index and PS refers to phase separation. RT refers to room temperature.