Table 4. Obstetric and neonatal outcomes in patients with LDoP.
| Outcome | ICP N= 26 |
PE with liver dysfunction N= 134 |
HELLP N= 72 |
AFLP N= 1 |
HG with liver dysfunction N= 14 |
Total N= 247 |
|---|---|---|---|---|---|---|
| OBSTETRIC OUTCOMES | ||||||
| Cesarian section | 4 (17%) | 68 (51%) | 34 (47%) | 1 (100%) | 1 (8%) | 108 (44%) |
| Premature delivery‡ | 1 (4%) | 75 (56%) | 50 (70%) | 1 (100%) | 2 (14%) | 129 (53%) |
| NEONATAL OUTCOMES | ||||||
| Infant death | 0 | 1 (0.7%) | 2 (3%) | 1 (100%) | 0 | 4 (1.6%) |
| Miscarriagea | 0 | 2 (1.5%) | 0 | 0 | 1 (7%) | 3 (1%) |
| Stillbirth* | 0 | 2 (1.5%) | 0 | 0 | 0 | 2 (0.8%) |
| Overall fetal mortality rate∞ | 0 | 5 (4%) | 2 (3%) | 1 (100%) | 1 (7%) | 9 (4%) |
| NICU admission | 0 | 42 (32%) | 31 (44%) | 1 (100%) | 0 | 74 (31%) |
| RECURRENT LDoP | ||||||
| % subjects with recurrent LDoP | 35% | 10% | 14% | 0 | 36% | 14% |
| % subsequent pregnancies with recurrent LDoP | 63% (10/16) | 12% (12/102) | 17% (11/63) | 0% (0/11) | 64% (7/11) | 21% (40/193) |
‡
Live delivery before 37 weeks gestation
a
Intrauterine death before 24 weeks gestation
*
Intrauterine death after 24 weeks gestation
∞
Includes infant death, miscarriage and stillbirth