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. Author manuscript; available in PMC: 2017 Jan 1.
Published in final edited form as: Psychiatry Clin Neurosci. 2015 Oct 8;70(1):51–61. doi: 10.1111/pcn.12357

Figure 3. Pre-Treatment Dorsal Anterior Cingulate and Posterior Medial Orbitofrontal Activation Negatively Correlated With Clinical Improvement.<.

Figure 3

br>Panels A–B depict correlational analyses of pre-treatment related effects on constraint and affective lability for the interaction [pre-treatment: (negative vs. neutral) × (no-go vs. go)] (Supplementary Table 2 and 4). Statistical parametric maps are thresholded at a voxelwise p-value of 0.01. Panel A shows an inverse correlation between pre-treatment activation in the right anterior-dorsal anterior cingulate cortex and post-treatment improvements in Multidimensional Personality Questionnaire (MPQ) – Constraint score (voxel-wise p-value < 0.001, corrected p-value=0.002). Panel B shows an inverse correlation between pre-treatment activation in the left posterior-medial orbitofrontal cortex/ventral striatum and post-treatment improvements in Affective Lability Scale (ALS) – Total score (voxel-wise p-value < 0.001, corrected p-value=0.013). X-axes formatted so that increasing values reflect clinical improvement.