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. Author manuscript; available in PMC: 2017 Feb 1.
Published in final edited form as: Chem Biol Drug Des. 2015 Sep 16;87(2):171–181. doi: 10.1111/cbdd.12651

Table 4.

Numerical results from fitting of the Hill equation (eqn 1) to Ca2+ titration curves for cTnT(T204E)-containing thin filament samples treated with Ca2+ sensitizer or control

cTnC–cTnI–cTnT(T204E) + Actin–
Tropomyosin (n = 5)		 pCa50 nH
Control 5.42 ± 0.10 1.36 ± 0.16
EMD 57033 5.45 ± 0.15 1.42 ± 0.28
Levosimendan 5.53 ± 0.10* 1.51 ± 0.12*
Bepridil 5.52 ± 0.13* 1.44 ± 0.14
Pimobendan 5.51 ± 0.16* 1.28 ± 0.35

Parameter standard deviation is given to the right of each parameter value.

*

Indicates a significant difference from wild type at the 95% level.