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. Author manuscript; available in PMC: 2017 Jan 19.
Published in final edited form as: Biochemistry. 2015 Dec 30;55(2):253–261. doi: 10.1021/acs.biochem.5b01171

Figure 2.

Figure 2

Effect of the variable linker region on PKR activation. (a) dsRNA-independent activation of hPKR and PKRΔV. (b) dsRNA-induced activation of PKRΔV. Activation was monitored at 0.1 µM PKRΔV with varying concentrations of 20 bp (black), 30 (blue) and 40 bp (red) dsRNA. The data are normalized relative to the extent of (wild-type) hPKR activation at 0.03 uM 40 bp dsRNA.