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. Author manuscript; available in PMC: 2016 Jun 14.
Published in final edited form as: Brain Imaging Behav. 2016 Jun;10(2):533–547. doi: 10.1007/s11682-015-9425-1

Figure 3.

Figure 3

Symmetrized Fractional Anisotropy White Matter Skeleton for a Single Reliability Dataset

Blue symmetrized white matter FA skeleton overlaid onto control plus subject group whole brain mean FA image from one reliability data library. This skeleton was created by first thickening the previous, asymmetric skeleton by one voxel. Then, this asymmetric mean FA image was flipped, averaged, and skeletonized to generate the initial symmetric skeleton. This initial symmetric skeleton was masked using the thickened asymmetric skeleton. This assured that only those structures already close to symmetric were used in this between-hemisphere analysis. In this way, structures that showed significant hemisphere-to-hemisphere differences were not overlaid and compared. Finally, to ensure symmetry, the skeleton was flipped and masked back to the non-flipped skeleton. This mean symmetrized skeleton was then thresholded (0.2) and each participant’s FA data was projected onto it.