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Deficiency of AnkB and Prx impairs myosin light chain (MLC) phosphorylation (pMLC) in the mouse lens. A–C: significantly decreased pMLC (A and B) and increased MLC (A and C) in AnkB−/+ lenses based on immunoblot quantification. GAPDH serves as a loading control. D–F: significantly decreased pMLC (D and E) and increased MLC (D and F) in Prx−/− lenses. Values in B, C, E, and F are means ± SE of 4 independent observations. *P < 0.05.
