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LY-2584702 prevents TGF-α-induced changes in lung mechanics. CCSP/TGF-α mice were administered Dox for 4 wk to induce pulmonary fibrosis and airway resistance, airway elastance, and lung compliance measured in mice treated with vehicle or LY-2584702. Data are means ± SE (n = 8–11 mice for each group), and statistical differences shown were performed using an unpaired t-test.
