Table 2.

Trajectories of cognitive decline according to comorbid depression and diabetes status

	Model One		Model Two		Model Three
Comorbidity Status	β̂	SE	β̂	SE	β̂	SE
Time	**−0.55	0.86	**−0.55	0.02	**−0.56	0.02
No depression, no diabetes (ref)	~	~	~	~	~	~
Depression, no diabetes	**−0.88	0.20	*−0.55	0.19	−0.33	0.18
Diabetes, no depression	0.20	0.19	*0.45	0.19	*0.41	0.17
Depression and diabetes	**−1.13	0.29	−0.28	0.28	−0.03	0.27
Comorbidity status x time
No depression, no diabetes (ref)	~	~	~	~	~	~
Depression, no diabetes	−0.08	0.05	−0.08	0.05	−0.11	*0.05
Diabetes, no depression	**−0.18	0.05	**−0.18	0.05	**−0.19	0.05
Depression and diabetes	**−0.25	0.08	**−0.25	0.08	**−0.26	0.09

Model one controlled for the effects of age, and educational attainment

Model two included the covariates from model one, nativity, smoking status, alcohol consumption status, marital status, number of residents living in the home, hypertension, heart disease, stroke, ability to perform ADLs and IADLs, and language.

Model three included all covariates from model two and excluded participants with baseline MMSE ≤ 17.

^*Statistical significance P < 0.05;

^**Statistical significance P < 0.01.

SE (Standard Error)